If you've gone looking for a way to disable or reset a user's two-factor authentication in Zoho CRM and can't find the option, or it doesn't seem to do anything, there are two likely causes worth checking, in order.
Zoho enforces domain verification specifically to protect sensitive user management actions, including Reset MFA, Disable MFA, Generate Backup Code, Create Mailbox, and Manage Email Address. These can only be performed for users whose email domain is verified within your organisation. If the affected user's domain hasn't been fully verified, the admin simply won't be able to action any of these for them, regardless of role or permission level.
If your organisation signs into Zoho CRM via Google Workspace, Microsoft Entra ID (Azure AD), or Okta through SAML/SSO, two-factor authentication is managed entirely within that third-party provider's own admin console, not within Zoho Directory or Zoho One at all. The Zoho-side MFA controls exist and are documented, but simply don't apply when SSO is the actual authentication method in use.
Go to your actual identity provider's own admin console, not Zoho's, to manage MFA for the affected user:
Once MFA is disabled or reset on the identity provider's side, the change takes effect the next time the user authenticates through SSO into Zoho CRM.